News

Innovative Technology to Combat STIs and BV in Africa

August 31, 2023

1 min read

Professor Jo-Ann Passmore from the University of Cape Town (UCT) is leading a research group that is developing technology to identify genital tract inflammation, even in cases without symptoms. This technology will help combat sexually transmitted infections (STIs) and bacterial vaginosis (BV).

The Research Group’s Work

The research group led by Passmore investigates inflammatory biomarkers in the genital tract and mucosal surface immunity that either protect against or increase susceptibility to STIs, including HPV and HIV. Their work spans various randomised controlled trials and cross-over studies that evaluate the impact of hormonal contraceptives on HIV risk in young South African women.

Challenges in Diagnosing STIs and BV

Limited access to healthcare services and high costs associated with STI-specific tests result in a reliance on diagnosing STIs and BV based on observable clinical signs and symptoms. A pressing concern arises from the substantial number of women and adolescent girls harboring STIs or BV without exhibiting any symptoms.

Higher Risk for Adolescent Girls and Young Women

Adolescent girls and young women aged 15-24 face a higher risk of HIV infection compared to their male counterparts. UNAIDS reported in 2022 that adolescent girls and young women in sub-Saharan Africa were three times more likely to contract HIV than males in the same age group.

Targeted Research for African Women

Professor Passmore said the underrepresentation of African participants in clinical trials hampers the development of targeted, practical, and relevant treatments for the continent. This lack of African data emphasizes the urgent need for targeted research to develop effective treatments for African women.

Comprehensive Approach to Tackling HIV in Africa

To address the elevated HIV infection rates and improve pregnancy outcomes in sub-Saharan Africa, Passmore calls for a comprehensive approach tackling the underlying issues. She believes that by integrating treatment for untreated STIs and BV, HIV incidence in Africa can be reduced.

Innovative Technology for Early Detection

Passmore and her UCT team are developing a cutting-edge technology involving a genital inflammation test using vaginal samples. This innovative method allows for early detection and intervention in cases of asymptomatic STIs and BV, consequently lowering the risk of HIV infection.

User-Friendly Design

Professor Passmore emphasized that this technology resembles an off-the-shelf pregnancy test in its non-invasive, cost-effective, and user-friendly design, making it an invaluable tool that can be quickly and easily administered in primary care settings or as part of home-based care.

Developing Targeted Interventions

By understanding the geographic variations in vaginal microbiomes underlying BV in Africa, the Vaginal Microbiome Research Consortium for Africa can develop targeted interventions tailor-made for African women and adolescent girls. This innovative approach holds tremendous potential in transforming the landscape of sexual and reproductive health in the African continent.

Shadows Along the Hennops: Three SAPS Officers Vanish and a River Gives Up Its Secrets

In April 2025, three South African police officers disappeared during a trip and were later found dead near the Hennops River, along with two others. Their white car vanished into the river’s dark, swirling waters, hiding clues and sparking a deep mystery. Families and the public mourned, demanding answers amid fears of foul play. The quiet river, once peaceful, now holds heavy secrets and reminds the nation of the dangers police face and the urgent need for justice.

cape town boatbuilding maritime industry

Cape Town’s Boatbuilding: Crafting a Legacy on the Waterfront

Cape Town’s boatbuilding industry is a shining example of skill and tradition mixed with new technology. It creates beautiful, strong boats that are loved worldwide and supports thousands of jobs in the city. But now, new tariffs on exports, especially to the US, threaten this important work and the people who depend on it. Despite these challenges, boatbuilders, city leaders, and innovators are coming together to protect this proud craft. Their passion and teamwork fuel hope that Cape Town’s boatbuilding legacy will sail on strong into the future.

Latest from Blog

vaping south african teenagers adolescent health risks

The Rise of Vaping Among South African Teenagers

Vaping is quickly becoming a popular habit among South African teenagers, drawn by sweet fruity flavors, flashy packaging, and the buzz on social media. Many teens vape to fit in with friends, feel cool and rebellious, or to escape stress and anxiety. However, what seems like harmless fun can quickly turn into addiction, affecting their health and wellbeing. Despite the risks, vaping is often misunderstood, making it harder for families and schools to stop this growing trend. It’s a serious challenge that needs everyone—parents, teachers, and leaders—to work together to protect young people’s futures.

south african agriculture agoa trade impact

South African Agriculture and the Changing Winds of Trade

Since 2000, the African Growth and Opportunity Act (AGOA) has helped South African farmers sell fruits like avocados, wine, and citrus to the United States without paying extra taxes. This chance boosted farming communities, especially small farmers and women, by opening up new markets and encouraging growth. But recent U.S. tariffs threaten these gains, making it harder for farmers to compete and putting many livelihoods at risk. Still, South African farmers remain strong and hopeful, working hard to face these new challenges and keep their communities alive.

Trapped Abroad: Ashley Oosthuizen’s Journey Through Thailand’s Legal Labyrinth

Ashley Oosthuizen, a young South African woman, went to Thailand chasing her dreams but ended up trapped in a nightmare. After unknowingly signing for a package with illegal drugs, she was arrested and sentenced to over 13 years in prison, despite being innocent. Her mother moved to Thailand to fight for her, sharing Ashley’s story with the world and gaining support. Even when the real criminal confessed, the Thai courts kept Ashley behind bars. Her story is a powerful reminder of how quickly life can change and the risks travelers face in foreign countries.

the ultimate mother city guide