The ISTAfrica Conference, organized by the Department of Science and Innovation (DSI) in South Africa, brought together public and private stakeholders to explore the role of information and communication technology (ICT) in addressing global challenges. Dr. Blade Nzimande, the South African Minister of Higher Education, Science and Innovation, emphasized the importance of international cooperation in science, technology, and innovation to provide innovative solutions for issues like climate change, food security, health, and energy.