Monkeypox, a virus related to smallpox, has evolved to include sexual transmission in addition to transmission through physical contact with infected animals, respiratory droplets, and scratches or bites. Symptoms include fever, rash, muscle aches, and swollen glands and can be fatal in severe cases. While treatments like Tecovirimat are available for severe cases, prevention through hand hygiene and seeking medical attention at the earliest sign of symptoms is critical to managing the spread of the disease. Monkeypox does not discriminate by gender, age, or sexual orientation.